Bertrand A, Roux J, Janbon F, Jourdan J, Jonquet O
Nouv Presse Med. 1979 Nov 12;8(44):3635-9.
The authors discuss the present value of rifampicin in the treatment of human brucellosis on the basis of: 1) a bacteriological study of 42 strains of Brucella spp. (MIC's of rifampicin, tetracyclin, doxycyclin, minocyclin and streptomycin; results of doxycyclin-rifampicin and doxycyclin-streptomycin combinations), and 2) a clinical study of 38 cases of brucellosis treated with rifampicin, including 25 acute septicemias and 13 osteo-arthritis. Satisfactory results were observed in 92% of the cases with rifampicin alone, but one cannot state that the benefits are significant.
1）对42株布鲁氏菌属菌株进行的细菌学研究（利福平、四环素、多西环素、米诺环素和链霉素的最低抑菌浓度；多西环素-利福平及多西环素-链霉素联合用药的结果），以及2）对38例接受利福平治疗的布鲁氏菌病患者进行的临床研究，其中包括25例急性败血症和13例骨关节炎患者。单独使用利福平治疗的病例中，92%观察到了满意的结果，但无法断言其益处显著。
