Lavie P
Biol Psychol. 1979 Jul;9(1):49-62. doi: 10.1016/0301-0511(79)90022-x.
Pupillary size, pupillary light reflex and pupillary motility were measured every 15 min, for 10 continuous hours, in eight young adults. Time series constructed from the range of pupillary motility revealed 75 to 125 min rhythms; these were significantly out of phase with rhythms of similar periodicity in pupillary diameter and in the magnitude of the pupillary light reflex. There was no consistent correspondence between Stanford Sleepiness Scores and pupillary activity. It is suggested that the rhythms in pupillary activity reflect underlying rhythms in CNS arousal that also modulate perceptual, cognitive and electroencephalographic processes, a conclusion which supports Kleitman's BRAC model.
对8名年轻成年人每隔15分钟测量一次瞳孔大小、瞳孔对光反射和瞳孔运动，持续10个小时。由瞳孔运动范围构建的时间序列显示出75至125分钟的节律；这些节律与瞳孔直径和瞳孔对光反射幅度中相似周期的节律明显不同步。斯坦福嗜睡评分与瞳孔活动之间没有一致的对应关系。研究表明，瞳孔活动的节律反映了中枢神经系统唤醒的潜在节律，这种节律也调节感知、认知和脑电图过程，这一结论支持了克莱特曼的BRAC模型。
