家兔体内四氯化碳的代谢
Carbon tetrachloride metabolism in the rabbit.
作者信息
Fowler J S
出版信息
Br J Pharmacol. 1969 Nov;37(3):733-7. doi: 10.1111/j.1476-5381.1969.tb08512.x.
Abstract
- Carbon tetrachloride was administered by stomach tube to rabbits and its distribution in fat, liver, kidney and muscle studied by gas liquid chromatography, during the next 48 hr.2. Chloroform, hexachloroethane and two unidentified chlorinated metabolites were detected in the tissues.3. Hexachloroethane may arise by dimerization of free trichloromethyl radicals.
摘要
通过胃管给兔子注射四氯化碳，并在接下来的48小时内用气相色谱法研究其在脂肪、肝脏、肾脏和肌肉中的分布。
在组织中检测到氯仿、六氯乙烷和两种未鉴定的氯化代谢物。
六氯乙烷可能由游离三氯甲基自由基二聚形成。
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