不饱和单羟基胆汁酸作为特发性阻塞性胆管病的一个病因
Unsaturated monohydroxy bile acids as a cause of idiopathic obstructive cholangiopathy.
作者信息
Jenner R E, Howard E R
出版信息
Lancet. 1975 Nov 29;2(7944):1073-5. doi: 10.1016/s0140-6736(75)90436-5.
PMID:53556
Abstract
It is proposed that some cases of biliary atresia and neonatal hepatitis may be initiated by an adverse effect of unsaturated monohydroxy bile acids on the fetal and infantile hepatobiliary system. The hypothesis is founded on morphological observations in patients with biliary atresia and on the toxic effects of monohydroxy bile acids on the hepatobiliary system.
摘要
有人提出，某些胆道闭锁和新生儿肝炎病例可能是由不饱和单羟基胆汁酸对胎儿和婴儿肝胆系统的不良影响引发的。这一假说基于对胆道闭锁患者的形态学观察以及单羟基胆汁酸对肝胆系统的毒性作用。
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