Kaneta H, Kujira K, Shigenaga T, Itaya K
Nihon Yakurigaku Zasshi. 1979 May;75(4):399-403. doi: 10.1254/fpj.75.399.
Norepinephrine (NE) content in the brain slightly but significantly increased when gamma-oryzanol (100 mg/kg, s.c.) was given once daily for 1, 5 or 10 days, while NE in the gastric area was not affected. The turnover rate of brain NE tended to decrease with the administration of gamma-oryzanol. From the results, it is likely that successive doses of gamma-oryzanol increase brain NE by inhibiting degradation or release of NE.
