Extensive sarcoidosis involving the upper respiratory tract.

Sarcoidosis is a multisystem granulomatous disease without pathognomonic symptomatology or pathology. It may involve the upper respiratory tract, but this manifestation is rarely threatening. A case is reported here, in which extensive destruction of the larynx due to involvement by sarcoidosis necessitated tracheostomy. A review of the literature and a discussion of the therapeutic considerations are presented.