Mráz J, Vrubel F, Hanselová M
Int Urol Nephrol. 1979;11(4):301-9. doi: 10.1007/BF02086817.
In 25 patients with carcinoma of the prostate (CaP) T3 and in a comparative group of 18 patients with BPH the serum enzymes of AP, tartrate labile AP, LDH, and iso-LDH were investigated simultaneously in basal conditions and after standardized transrectal prostatic biopsy. AP, PAP as well as LDH were shown to be of small diagnostic aid. The reaction of serum enzyme levels following the standardized prostatic biopsy was the same in both CaP and BPH patients. In studying LDH-isoenzymes, we found that the third fraction was elevated in almost all patients. This change is apparently not of prostatic origin, and we could not attribute it to the concomitant diseases found in some patients.
对25例前列腺癌（CaP）T3期患者以及18例良性前列腺增生（BPH）患者组成的对照组，在基础状态下以及标准化经直肠前列腺活检后，同时检测血清碱性磷酸酶（AP）、抗酒石酸酸性磷酸酶（tartrate labile AP）、乳酸脱氢酶（LDH）及其同工酶（iso-LDH）。结果显示，AP、前列腺酸性磷酸酶（PAP）以及LDH的诊断价值较小。标准化前列腺活检后，CaP患者和BPH患者血清酶水平的变化相同。在研究LDH同工酶时，我们发现几乎所有患者的第三组分均升高。这种变化显然并非源于前列腺，我们也不能将其归因于部分患者所患的伴发疾病。
