Grayhack J T, Wendel E F, Lee C, Oliver L
Cancer Treat Rep. 1977 Mar-Apr;61(2):205-10.
The current studies of expressed prostatic fluid tend to confirm our previous reported pilot observations of a shift in lactic dehydrogenase (LDH) isoenzymes to a predominance of LDHV in patients with prostatic malignancy. They also suggest a decrease in concentration of acid phosphatase and an increase in concentration of protein in the presence of carcinoma of the prostate. These observations suggest a diffuse metabolic alteration of the prostate in the presence of prostatic carcinoma.
目前对前列腺液的研究倾向于证实我们之前报告的初步观察结果,即前列腺恶性肿瘤患者中乳酸脱氢酶(LDH)同工酶转变为以LDHV为主。这些研究还表明,前列腺癌患者酸性磷酸酶浓度降低,蛋白质浓度升高。这些观察结果表明前列腺癌发生时前列腺存在弥漫性代谢改变。