Barzanji J, Emery J L
J Anat. 1979 Dec;129(Pt 4):819-22.
The spleens of 124 anatomically normal weight-for-age fetuses and 115 term babies dying between birth and four weeks have been assessed histologically. The mean weight of the spleen shows a steady increase from 27 weeks of gestation up to 42 weeks. There is a weight loss of about 4 gm at the time of birth. The weight of the spleen increases steadily in neonates and, by the fourth week, it reaches the same weight as the full term stillbirth. The amount of lymphatic tissue in the spleen increases steadily in the stillbirths of different gestations and continues, without interruption, at the time of birth and in neonates. The weight loss of the spleen at birth can only be accounted for on the basis of a reduction in the blood lake of the pulp.
对124例解剖学上正常、体重与年龄相符的胎儿以及115例出生至4周内死亡的足月儿的脾脏进行了组织学评估。脾脏的平均重量从妊娠27周直至42周呈稳步增加。出生时脾脏重量约减轻4克。新生儿期脾脏重量稳步增加，到第4周时，其重量达到与足月死产儿相同的水平。在不同孕周的死产儿中，脾脏内淋巴组织的数量稳步增加，并在出生时和新生儿期持续不间断地增加。出生时脾脏重量的减轻只能基于脾髓血池的减少来解释。
