Barzanji A J, Emery J L
Early Hum Dev. 1978 Feb;1(4):363-9. doi: 10.1016/0378-3782(78)90044-0.
Sections of spleens from 235 stillbirths and 227 babies who died between the ages of 1 and 35 days were examined. None of the stillbirths showed any germinal centres, neither did the spleens of any of the babies who died between the ages of 1 and 14 days. From the age of 15 days onwards, the germinal centres started to appear in varying numbers. The appearance of germinal centres in the spleen is further delayed in infants born before 37 wk gestation. Germinal centres in the spleen in neonates do not appear to be related to the presence of inflammatory changes elsewhere in the infant.
对235例死产儿以及227例1至35日龄死亡婴儿的脾脏切片进行了检查。所有死产儿的脾脏均未显示任何生发中心，1至14日龄死亡婴儿的脾脏也未显示生发中心。从15日龄起，生发中心开始以不同数量出现。孕37周前出生的婴儿脾脏中生发中心的出现进一步延迟。新生儿脾脏中的生发中心似乎与婴儿其他部位炎症变化的存在无关。
