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胃肠道癌症与营养

Gastrointestinal cancer and nutrition.

作者信息

Gregor O, Toman R, Prusová F

出版信息

Gut. 1969 Dec;10(12):1031-4. doi: 10.1136/gut.10.12.1031.

Abstract

The hypothesis upon which this study was based is that there is a relationship between mortality from gastrointestinal cancer and living standards. On this basis we found significant correlations between the intake of animal proteins and the mortality rates for gastric and intestinal cancer. The negative correlation coefficient (r = - 0.85) is an expression of the inverse relationship between gastric and intestinal cancer mortality rates. This inverse relationship is also expressed as the correlation between the food intake, expressed by the intake of animal protein, and the respective mortality rates. The higher the food intake, the lower the gastric cancer mortality rate but the higher the intestinal cancer mortality rate. We do not claim that this relationship discovered by correlation analysis is a causal one. On the basis of this study it cannot therefore be said that food intake has a direct effect on the development of gastrointestinal cancer. In this respect our findings can only be a signal for further studies. Secondly no time lag has been proved between food intake and the mortality rate for intestinal cancer. The findings relating to gastric cancer do not contradict the hypothesis of a time lag.

摘要

本研究基于这样一个假设,即胃肠道癌症死亡率与生活水平之间存在关联。在此基础上,我们发现动物蛋白摄入量与胃癌和肠癌死亡率之间存在显著相关性。负相关系数(r = - 0.85)表明胃癌和肠癌死亡率之间呈反比关系。这种反比关系也表现为以动物蛋白摄入量表示的食物摄入量与各自死亡率之间的相关性。食物摄入量越高,胃癌死亡率越低,但肠癌死亡率越高。我们并不认为通过相关分析发现的这种关系是因果关系。因此,基于本研究不能说食物摄入量对胃肠道癌症的发展有直接影响。在这方面,我们的发现只能作为进一步研究的一个信号。其次,尚未证明食物摄入量与肠癌死亡率之间存在时间滞后。与胃癌相关的研究结果并不与时间滞后的假设相矛盾。

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