Ruff W L, Duhaney S D, Kim J J
J Natl Med Assoc. 1979 Oct;71(10):971-6.
Sixteen normal individuals and 100 hospital patients, all black, were tested for abnormal carcinoembryonic antigen (CEA) levels. Male and female subjects (smokers and non-smokers) were tested. The results of the tests are discussed. For normal subjects, the CEA values ranged from 0.0 ng/ml to 2.6 ng/ml. Among hospital patients with neoplastic disease, male patients with lung disease showed elevated CEA titers but their female counterparts did not. On the other hand, female patients with breast cancer, in contrast to their male counterparts, had raised values of CEA. The clinical indices for laboratory tests of sensitivity, specificity, and predictive value were calculated and determined to be 71.5, 56, and 47.5 percent, respectively.
对16名正常个体和100名均为黑人的住院患者进行了癌胚抗原(CEA)异常水平检测。对男性和女性受试者(吸烟者和非吸烟者)进行了检测。讨论了检测结果。正常受试者的CEA值范围为0.0纳克/毫升至2.6纳克/毫升。在患有肿瘤疾病的住院患者中,患有肺部疾病的男性患者CEA滴度升高,但其女性对应患者未出现这种情况。另一方面,患有乳腺癌的女性患者,与其男性对应患者相比,CEA值升高。计算了实验室检测的敏感性、特异性和预测值的临床指标,分别确定为71.5%、56%和47.5%。