Armstrong B, Joske R A
Natl Cancer Inst Monogr. 1979 Nov(53):127-32.
The incidence of PLC in the Pacific Basin varies from 0.9/100,000 (age-standardized) in women in New South Wales, Australia, to 34.2/100,000 in Singapore Chinese men. Proportional incidence data suggest that other areas of the Pacific Basin, such as Hong Kong, Taiwan, Indonesia, and Papua New Guinea, may have PLC incidence rates as high or higher than those in Singapore Chinese. Infection with hepatitis-B virus has been associated with PLC in some areas, and aflatoxin contamination of food has also been demonstrated. The extent to which these or other factors explain the geographical variation in liver cancer rates in the Pacific Basin is uncertain.
太平洋地区原发性肝癌（PLC）的发病率有所不同，在澳大利亚新南威尔士州女性中为0.9/10万（年龄标准化），而在新加坡华裔男性中为34.2/10万。比例发病率数据表明，太平洋地区的其他一些地区，如中国香港、台湾、印度尼西亚和巴布亚新几内亚，原发性肝癌发病率可能与新加坡华裔相当或更高。在一些地区，乙型肝炎病毒感染与原发性肝癌有关，并且食物中的黄曲霉毒素污染也已得到证实。这些因素或其他因素在多大程度上解释了太平洋地区肝癌发病率的地理差异尚不确定。
