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[针刺作为阿片类药物解毒及脱毒方案的一部分:25例]

[Acupuncture as a part of a program of detoxification and weaning from opiates: 25 cases].

作者信息

Lorini G, Fazio L, Cocchi R, Fusari A, Roccia L

出版信息

Minerva Med. 1979 Dec 15;70(56):3831-6.

PMID:537697
Abstract

Presents results of a detoxification and habit loosing program carried out in 25 morphine-like substances addicts (mainly heroine) aged 19-26. The therapeutic treatment based on gabaergic drugs (l-glutamine, sodium valproate and piridoxine), low doses psychodrugs (tricyclics and benzodiacepines) and acupuncture, began in 13 subjects at the hospital and continued at the outpatients' service, while 12 subjects were treated only at the outpatients' service. Follow up: 6 subjects of the hospitalized group free from the addiction (5 subjects from more than 1 year after their discharge); 3 subjects of the outpatients' group abstinent from no more than 4 months after discharge. Biochemical mechanisms involved in this therapeutic program are extensively discussed.

摘要

介绍了一项针对25名年龄在19至26岁的吗啡样物质成瘾者(主要是海洛因成瘾者)开展的戒毒和戒除习惯项目的结果。治疗方法基于γ-氨基丁酸能药物(L-谷氨酰胺、丙戊酸钠和吡哆醇)、低剂量精神药物(三环类药物和苯二氮䓬类药物)以及针灸,13名受试者在医院开始治疗,并在门诊继续治疗,而12名受试者仅在门诊接受治疗。随访情况:住院组中有6名受试者戒除了成瘾(5名受试者在出院后1年以上);门诊组中有3名受试者在出院后戒除时间不超过4个月。文中对该治疗项目所涉及的生化机制进行了广泛讨论。

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