Strian F, Albert W, Klicpera C
Pharmakopsychiatr Neuropsychopharmakol. 1979 Nov;12(6):432-7. doi: 10.1055/s-0028-1094640.
In 105 patients with endogenous depression treated with antidepressants or ECT the course of the depressive state was evaluated by means of a self-rating mood scale (Befindlichkeits-Skala by von Zerssen). The scale was filled out every second day. The course of the depressive mood was computed by various algorithms for each patient. Two different courses of depressive mood could be identified: some patients showed a relatively continuous decline in the depressive mood, whereas others showed strong fluctuations. Although there were some correlations between type of treatment and extent of mood swings, other factors also seemed to be relevant. Thus, there appears to be an interaction between treatment effects and spontaneous rhythms.
在105例接受抗抑郁药或电休克治疗的内源性抑郁症患者中，通过自评情绪量表（冯·泽尔森的情绪状态量表）评估抑郁状态的病程。该量表每隔一天填写一次。针对每位患者，通过各种算法计算抑郁情绪的病程。可以识别出两种不同的抑郁情绪病程：一些患者的抑郁情绪呈现相对持续的下降，而另一些患者则表现出强烈的波动。尽管治疗类型与情绪波动程度之间存在一些相关性，但其他因素似乎也很重要。因此，治疗效果与自发节律之间似乎存在相互作用。
