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1
Gastrointestinal motility and gastric secretion during intravenous infusions of gastrin II.静脉输注胃泌素II期间的胃肠动力和胃液分泌。
Gut. 1969 Sep;10(9):723-9. doi: 10.1136/gut.10.9.723.
2
Motor responses of the human alimentary tract to near-maximal infusions of pentagastrin.人体消化道对近最大剂量五肽胃泌素输注的运动反应。
Gut. 1967 Oct;8(5):463-9. doi: 10.1136/gut.8.5.463.
3
The role of gastrin in gastroileocolic responses.胃泌素在胃肠回结肠反应中的作用。
Am J Dig Dis. 1967 Mar;12(3):277-84. doi: 10.1007/BF02233645.
4
Effect of graded doses of pentagastrin, histamine and 2-deoxy-D-glucose on gastric secretion and motility in conscious rats.不同剂量的五肽胃泌素、组胺和2-脱氧-D-葡萄糖对清醒大鼠胃分泌和运动的影响。
Scand J Gastroenterol. 1968;3(6):572-6.
5
Effects of gastrin I, secretin and cholecystokinin-pancreozymin on the electrical activity, motor activity, and acid output of the stomach in man.胃泌素I、促胰液素和缩胆囊素-促胰酶素对人体胃电活动、运动活性及胃酸分泌的影响。
Scand J Gastroenterol. 1972;7(2):161-70.
6
Action of gastrin on the lower oesophageal sphincter in man.胃泌素对人食管下括约肌的作用。
Gut. 1969 Sep;10(9):730-4. doi: 10.1136/gut.10.9.730.
7
Effect of gastrin and SC 15396 on gastric motility in dogs.胃泌素和SC 15396对犬胃动力的影响。
Gastroenterology. 1969 Mar;56(3):450-5.
8
Comparison of the stimulating effects of gastrin and histamine on the gastric secretion of rats.胃泌素与组胺对大鼠胃液分泌刺激作用的比较。
Acta Pharmacol Toxicol (Copenh). 1967;25(4):420-6. doi: 10.1111/j.1600-0773.1967.tb00410.x.
9
The effect of glucagon on cholinomimetic responses of the recto-sigmoid.胰高血糖素对直肠乙状结肠拟胆碱反应的影响。
G E N. 1976 Jul-Dec;31(1-2):5-10.
10
Gastrin, cholecystokinin, and secretin act on one receptor.胃泌素、胆囊收缩素和促胰液素作用于同一受体。
Lancet. 1970 May 23;1(7656):1088-9. doi: 10.1016/s0140-6736(70)92758-3.

引用本文的文献

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Effects of Tegoprazan, Potassium-Competitive Acid Blocker, on the Gastric Emptying and Postprandial Symptoms in Healthy Humans.钾离子竞争性酸阻滞剂替戈拉赞对健康人胃排空及餐后症状的影响。
Dig Dis Sci. 2025 Mar;70(3):1091-1098. doi: 10.1007/s10620-024-08714-0. Epub 2024 Nov 18.
2
Colonic motility: practice or research?结肠动力:实践还是研究?
Gut. 1993 Aug;34(8):1009-12. doi: 10.1136/gut.34.8.1009.
3
Factors controlling colonic motility: colonic pressures and transit after meals in patients with total gastrectomy, pernicious anaemia or duodenal ulcer.控制结肠运动的因素:全胃切除术、恶性贫血或十二指肠溃疡患者餐后的结肠压力与转运
Gut. 1970 Feb;11(2):100-10. doi: 10.1136/gut.11.2.100.
4
Gastrin and gastrointestinal disease.胃泌素与胃肠疾病。
Br Med J. 1972 Nov 4;4(5835):297. doi: 10.1136/bmj.4.5835.297.
5
Effects of oral magnesium sulphate on colonic motility in patients with the irritable bowel syndrome.口服硫酸镁对肠易激综合征患者结肠动力的影响。
Gut. 1973 Dec;14(12):983-7. doi: 10.1136/gut.14.12.983.
6
Colonic motility in man.人类的结肠运动
Postgrad Med J. 1973 Feb;49(568):90-9. doi: 10.1136/pgmj.49.568.90.
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The irritable colon.过敏性结肠
Can Med Assoc J. 1974 Dec 7;111(11):1236, 1241-4.
8
[The influence of petagastrin on the gastro-esophageal sphincter. An experimental study in animals (author's transl)].[五肽胃泌素对胃食管括约肌的影响。动物实验研究(作者译)]
Langenbecks Arch Chir. 1974;336(3):235-46. doi: 10.1007/BF01261651.
9
Hormonal control of gastrointestinal motility.胃肠道蠕动的激素调控
Am J Dig Dis. 1975 Jun;20(6):523-39. doi: 10.1007/BF01074937.
10
Colonic motility.结肠动力
Gut. 1975 Apr;16(4):311-4. doi: 10.1136/gut.16.4.311.

本文引用的文献

1
PHYSIOLOGICAL PROPERTIES OF A SERIES OF SYNTHETIC PEPTIDES STRUCTURALLY RELATED TO GASTRIN I.一系列与胃泌素I结构相关的合成肽的生理特性
Nature. 1964 Dec 5;204:935-8. doi: 10.1038/204935a0.
2
DOSE-RESPONSE CURVES FOR THE EFFECT OF GASTRIN II ON ACID GASTRIC SECRETION IN MAN.胃泌素II对人胃酸分泌作用的剂量反应曲线。
Gut. 1964 Oct;5(5):379-84. doi: 10.1136/gut.5.5.379.
3
Analysis of the motor effects of gastrin and pentagastrin on the human alimentary tract in vitro.胃泌素和五肽胃泌素对人体消化道运动作用的体外分析。
Gut. 1967 Oct;8(5):470-4. doi: 10.1136/gut.8.5.470.
4
Motor responses of the human alimentary tract to near-maximal infusions of pentagastrin.人体消化道对近最大剂量五肽胃泌素输注的运动反应。
Gut. 1967 Oct;8(5):463-9. doi: 10.1136/gut.8.5.463.
5
Effect of gastrin II on gastric emptying and secretion during a test meal.胃泌素II对试餐期间胃排空和分泌的影响。
Br Med J. 1967 Nov 18;4(5576):386-7. doi: 10.1136/bmj.4.5576.386.
6
Comparison of the rates of gastric acid secretion in man after ingestion of food and after maximal stimulation with histamine.人体摄入食物后与用组胺最大刺激后胃酸分泌速率的比较。
Gut. 1966 Aug;7(4):344-50. doi: 10.1136/gut.7.4.344.
7
Physiological role of gastrin.
Fed Proc. 1968 Nov-Dec;27(6):1312-3.
8
A study of human gall bladder muscle in vitro.一项人体胆囊肌肉的体外研究。
Gut. 1968 Oct;9(5):546-9. doi: 10.1136/gut.9.5.546.
9
The actions of caerulein on the smooth muscle of the gastrointestinal tract and the gall bladder.蛙皮素对胃肠道和胆囊平滑肌的作用。
Br J Pharmacol. 1968 Oct;34(2):291-310. doi: 10.1111/j.1476-5381.1968.tb07052.x.
10
Cholecystokinetic potency of gastrointestinal hormones and related peptides.胃肠激素及相关肽的胆囊运动效能
Am J Physiol. 1968 Oct;215(4):881-4. doi: 10.1152/ajplegacy.1968.215.4.881.

静脉输注胃泌素II期间的胃肠动力和胃液分泌。

Gastrointestinal motility and gastric secretion during intravenous infusions of gastrin II.

作者信息

Misiewicz J J, Waller S L, Holdstock D J

出版信息

Gut. 1969 Sep;10(9):723-9. doi: 10.1136/gut.10.9.723.

DOI:10.1136/gut.10.9.723
PMID:5386629
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1552979/
Abstract

The effect of intravenous infusion of gastrin II on gastric and colonic motor activity was studied in 12 patients; gastric acid output was also measured. Administration of gastrin at near-maximal dose levels stimulates the motor activity of the antrum but has no measurable effect on the activity of the proximal colon, sigmoid, or rectum. The results suggest that gastrin plays a part in the regulation of gastric motility but that it is not a mediator of the gastro-colic reflex.

摘要

对12例患者研究了静脉输注胃泌素II对胃和结肠运动活性的影响;同时也测定了胃酸分泌量。给予接近最大剂量水平的胃泌素可刺激胃窦的运动活性,但对近端结肠、乙状结肠或直肠的活性无显著影响。结果提示,胃泌素在胃动力调节中起作用,但它不是胃结肠反射的介质。