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使用宫缩抑制剂会导致心肌损伤吗?(作者译)

[Does myocardial damage arise as a result of administration of tocolytic drugs? (author's transl)].

作者信息

Lechner W, Dienstl F

出版信息

Wien Klin Wochenschr. 1979 Dec 7;91(23):798-801.

PMID:538935
Abstract

Fifty pregnant women admitted consecutively on account of threatened abortion or premature labour and treated with Ritodrine and Verapamil intravenously in the usual dosage were investigated with respect to creatine kinase activity and, in the event of a raised level, its isoenzyme creatine kinase--MB. Determinations were carried out before treatment and, in accordance with expected peak values in case of myocardial necrosis, after 6 and 12 hours. Three pathological values were recorded and these are discussed individually. Furthermore, statistical evaluation of the recorded values showed no significant differences.

摘要

对50例因先兆流产或早产而连续入院、并按常规剂量静脉注射利托君和维拉帕米进行治疗的孕妇,就肌酸激酶活性进行了研究,若该水平升高,则对其同工酶肌酸激酶-MB进行研究。在治疗前以及根据心肌坏死情况下预期的峰值,在6小时和12小时后进行测定。记录了3个病理值,并对这些值进行了单独讨论。此外,对记录值的统计评估显示无显著差异。

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