Szarvas Z
Zentralbl Gynakol. 1979;101(20):1323-8.
The use of progestagenic hormones in the treatment of endometrial carcinoma is reported in this paper. Optical microscopy and ultrastructural techniques used in morphological investigation established extremely good response to treatment primarily by adenocarcinomas which are characterised by advanced histologic differentiation. Deceleration of tumour progression was a clinical result of the therapeutic approach taken, with shorter or longer periods of remission being recordable. The results are likely to support the assumption that "cytostatic" action of progestagenic substances can yield desirable complementary effects in cases when surgical or radiological treatment is abandoned for high risk.
本文报道了孕激素类激素在子宫内膜癌治疗中的应用。形态学研究中使用的光学显微镜和超微结构技术证实,主要针对具有高级别组织学分化特征的腺癌,治疗反应极佳。肿瘤进展减缓是所采用治疗方法的临床结果,可记录到长短不一的缓解期。这些结果可能支持这样一种假设,即当因高风险而放弃手术或放射治疗时,孕激素类物质的“细胞抑制”作用可产生理想的辅助效果。