Punnonen R, Aho A J, Grönroos M, Liukko P
Acta Chir Scand. 1979;145(8):555-8.
Twenty-four appendicectomies were performed during intra-uterine pregnancy at the Department of Surgery of the University Central Hospital, Turku, in the period 1963--77. Six out of 14 cases of appendicitis occurred in the third trimester. The incidence of appendicitis during pregnancy was 1 : 1 445. In 9 cases the appendices removed were normal. The diagnostic difficulties were greatest during the final phase of pregnancy. The location of palpation tenderness in these cases differed from that in the cases with a normal appendix. Fever was generally slight and was sometimes completely absent. The appendix had perforated in 2 cases in both of which premature delivery occurred on the third postoperative day. The infant died in one of these two cases because of immaturity. The pregnancy of the other patients continued uneventfully to term. Appendicitis and appendecectomy performed in good time generally do not involve risk for the continued progress of pregnancy. Progesterone or isoxuprine may have beneficial effect on the course of the pregnancy.
1963年至1977年期间，图尔库大学中心医院外科为24例宫内妊娠患者实施了阑尾切除术。14例阑尾炎患者中有6例发生在妊娠晚期。妊娠期阑尾炎的发病率为1∶1445。9例切除的阑尾外观正常。妊娠末期诊断困难最大。这些病例中触痛的部位与阑尾正常的病例不同。发热一般较轻，有时完全不发热。2例阑尾已穿孔，均在术后第3天发生早产。这两例中有1例婴儿因未成熟而死亡。其他患者的妊娠均顺利持续至足月。及时进行阑尾炎手术和阑尾切除术一般不会对妊娠的继续发展构成风险。黄体酮或异克舒令可能对妊娠过程有有益影响。
