Peshleĭski P
Vet Med Nauki. 1975;12(10):78-82.
Studied was the effect of a serum paratyph and Aujeszky gammaglobulin injected 10, 15, and 20 days prior to the crystal-violet and the lapinized vaccine. If the animals were infected with a pathogenic swine fever virus 10 to 15 days after their treatment with serum at the rate of 0.5 cu. cm per kg, part of them died, and the remaining contracted the disease showing a protracted course. The control vaccination on the 20th day after the animals were injected with serum led to the death of all of them showing the signs of acute swine fever. Most of the pigs injected with 5 cu. cm gamma-globulin each and 10--15 days later being infected with a swine fever virus manifested the disease, however, none of them died of the disease. If, however, after treatment with gamma-globulin they were challenged on the 20th day all of them died of acute swine fever. In the immunization of pigs with a crystal-violet vaccine on the 14th day of their treatment with Aujeszky gamma-globulin, part of them developed an atypical form of the disease, while most of them did not show symptoms whatever of swine fever. Of the immunized with a lapinized vaccine some died, and the remaining part did not contract the disease at all. All this pointed to the fact that the residual antibodies against swine fever contained in the specific Aujeszky gamma-globulin could still be in a position to inhibit the vaccinal virus, and more specifically that of the lapinized K vaccine. The vaccination against swine fever should be performed 14 days after the injection of the serum paratyph and about 20 days after the injection of the Aujeszky gammaglobulin.
研究了在接种结晶紫疫苗和兔化疫苗前10天、15天和20天注射副伤寒和奥耶斯基γ球蛋白血清的效果。如果动物在以每公斤0.5立方厘米的剂量用血清治疗后10至15天感染致病性猪瘟病毒，部分动物死亡，其余动物感染疾病且病程迁延。在动物注射血清后第20天进行对照疫苗接种，所有动物均死亡，呈现急性猪瘟症状。大多数每只注射5立方厘米γ球蛋白且10 - 15天后感染猪瘟病毒的猪表现出疾病症状，但无一死亡。然而，如果在γ球蛋白治疗后第20天对它们进行攻毒，所有动物均死于急性猪瘟。在用奥耶斯基γ球蛋白治疗猪的第14天用结晶紫疫苗免疫，部分猪出现非典型疾病形式，而大多数猪未表现出任何猪瘟症状。在用兔化疫苗免疫的猪中，部分死亡，其余部分根本未感染疾病。所有这些都表明，特异性奥耶斯基γ球蛋白中所含的抗猪瘟残留抗体仍能够抑制疫苗病毒，更具体地说是兔化K疫苗病毒。猪瘟疫苗接种应在注射副伤寒血清后14天进行，在注射奥耶斯基γ球蛋白后约20天进行。
