Embryotoxicity and teratogenicity of styrene and styrene oxide on chick embryos enhanced by trichloropropylene oxide.
作者信息
Kankaanpää J T, Hemminki K, Vainio H
出版信息
Acta Pharmacol Toxicol (Copenh). 1979 Nov;45(5):399-402. doi: 10.1111/j.1600-0773.1979.tb02408.x.
Abstract
The effects of TCPO (trichloropropylene oxide) on the embryotoxicity and teratogenicity of styrene and styrene oxide and chick embryos were investigated. The compounds were injected into the air space of the eggs in a total volume of 25 microliter on the third day of embryogenesis. TCPO increased embryotoxicity and teratogenicity of styrene and styrene oxide. Our results present evidence that the epoxides possess embryotoxic and teratogenic properties in chick embryos.
摘要
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