急性苯丙胺滥用。神经外科手术全身麻醉期间的问题。
Acute amphetamine abuse. Problems during general anaesthesia for neurosurgery.
作者信息
Michel R, Adams A P
出版信息
Anaesthesia. 1979 Nov-Dec;34(10):1016-9. doi: 10.1111/j.1365-2044.1979.tb06250.x.
Abstract
A case of unsuspected acute amphetamine abuse by a 22-year-old girl which led to serious intracranial hypertension during anaesthesia for a neurosurgical procedure is described. It was difficult to maintained anaesthesia with an intermittent positive-pressure ventilation technique using muscle relaxants, N2O and O2 and supplements of fentanyl despite large doses of pancuronium and fentanyl. The differing effects of chronic and acute amphetamine dosage on anaesthetic requirements are reviewed.
摘要
本文描述了一名22岁女孩意外急性滥用安非他明的病例，该病例导致其在神经外科手术麻醉期间出现严重的颅内高压。尽管使用了大剂量的泮库溴铵和芬太尼，但采用间歇正压通气技术、肌肉松弛剂、笑气和氧气并补充芬太尼来维持麻醉仍很困难。本文还综述了慢性和急性安非他明剂量对麻醉需求的不同影响。
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