伪装成面部肉芽肿的皮肤淋巴瘤。

Cutaneous lymphoma masquerading as granuloma faciale.

作者信息

Noe J M, Sober A H, Fein S H, Grendell J H, Sasken H

出版信息

Ann Plast Surg. 1979 Oct;3(4):361-7. doi: 10.1097/00000637-197910000-00012.

DOI:10.1097/00000637-197910000-00012

Abstract

Granuloma faciale is a presumably benign disorder of the skin--usually of the face--characterized by a dense, polymorphous, inflammatory infiltrate including numerous eosinophils, separated from the epidermis by a clear or "grenz" zone, and possessing a small vessel, leukocytoclastic vasculitis. Primary malignant lymphoma of the skin, other than mycosis fungoides, is an unusual entity that may follow a widely variable course and is often extremely difficult to diagnose definitively. A patient is presented in whom a lesion consistent with granuloma faciale changed its histological appearance and clinical behavior into that of a malignant lymphoma.

摘要

面部肉芽肿是一种推测为良性的皮肤疾病——通常发生于面部——其特征为致密、多形性的炎性浸润，包括大量嗜酸性粒细胞，与表皮之间有一个透明或“无浸润”带分隔，并伴有小血管白细胞破碎性血管炎。除蕈样肉芽肿外，原发性皮肤恶性淋巴瘤是一种不常见的疾病，其病程可能差异很大，而且往往极难明确诊断。本文报告1例患者，其最初表现为符合面部肉芽肿的皮损，但其组织学表现和临床行为后来转变为恶性淋巴瘤。