Barrio R, Roger M, Chaussain J L, Job J C
Arch Fr Pediatr. 1979 Sep-Oct;36(8):785-93.
Eight adolescent patients, 4 boys and 4 girls with prolactin secreting pituitary adenomas have been studied. The first symptoms developed between the ages of 8 and 14 years. The main complaints were headache (7 cases), delay or failure of growth (6 cases) or of puberty (3 cases), and amenorrhoea with galactorrhoea (2 cases). The diagnosis could be made easily from the enlarged sella turcica and the high plasma prolactin levels. Anterior pituitary insufficiency is variable. Persistent hyperprolactinaemia after surgery may require treatment with bromocriptine.
对8例青少年催乳素分泌型垂体腺瘤患者进行了研究,其中4例男孩,4例女孩。首发症状出现在8至14岁之间。主要症状为头痛(7例)、生长发育延迟或停滞(6例)、青春期发育延迟(3例)、闭经伴溢乳(2例)。根据蝶鞍扩大及血浆催乳素水平升高,诊断并不困难。垂体前叶功能减退程度不一。术后持续高催乳素血症可能需用溴隐亭治疗。