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尼麦角林在动脉高血压和慢性脑血管功能不全症状性治疗中的作用。359例观察研究(作者译)

[The role of nicergoline in the symptomatic treatment of arterial hypertension and chronic cerebrovascular insufficiency. A study on 359 observations (author's transl)].

作者信息

Dauverchain J

出版信息

Arzneimittelforschung. 1979;29(8a):1308-10.

PMID:395956
Abstract

An examination was carried out on the efficacy of 10-methoxy-1,6-diemethyl-ergoline-8 beta-methanol-(5-bromonicotinate) (nicergoline, Sermion) on the symptoms of functional side effects of arterial hypertension and chronic circulatory insufficiency as regards the psychomotoric activity and the relational activity; 359 patients suffering from crebrovascular insufficiency were included in the study. The compound was applied in a daily dose of 10 mg i. m. for 5 days and then in a daily dose of 15 mg orally for 1 month. In the entire symptom complex of cerebro-vascular insufficiency a positive effect of nicergoline could be observed; the results of all clinical criteria and their therapeutic relevance are discussed.

摘要

对10-甲氧基-1,6-二甲基-麦角灵-8β-甲醇-(5-溴烟酸酯)(尼麦角林,喜得镇)治疗动脉高血压和慢性循环功能不全功能性副作用症状的疗效进行了一项研究,涉及精神运动活动和关联活动;359例脑血管功能不全患者纳入研究。该化合物以每日10mg的剂量肌肉注射,持续5天,然后以每日15mg的剂量口服,持续1个月。在脑血管功能不全的整个症状复合体中,可以观察到尼麦角林的积极作用;讨论了所有临床标准的结果及其治疗相关性。

相似文献

1
[The role of nicergoline in the symptomatic treatment of arterial hypertension and chronic cerebrovascular insufficiency. A study on 359 observations (author's transl)].尼麦角林在动脉高血压和慢性脑血管功能不全症状性治疗中的作用。359例观察研究(作者译)
Arzneimittelforschung. 1979;29(8a):1308-10.
2
[Neurophysiological study of 36 patients with cerebral vascular processes treated with nicergoline (author's transl)].尼麦角林治疗36例脑血管疾病患者的神经生理学研究(作者译)
Arzneimittelforschung. 1979;29(8a):1301-7.
3
[Psychopathometric double blind study with nicergoline versus placebo in geriatric patients with slight transit syndromes].[尼麦角林与安慰剂治疗轻度转运综合征老年患者的精神心理测量双盲研究]
Arzneimittelforschung. 1979;29(8a):1295-301.
4
[Interaction between anti-aggregating and anticoagulant agents. A double blind study on the concomitant administration of nicergoline and acenocoumarols].
Arzneimittelforschung. 1979;29(8a):1266-9.
5
[Treatment of arterial hypertension in the elderly with an alpha-blocker: nicergoline (author's transl)].
Nouv Presse Med. 1980 Dec 20;9(48):3685-8.
6
[Electroencephalography and psychometric measurements during the treatment of cerebral insufficiency with nicergoline and dihydroergotamine mesylate].
Arzneimittelforschung. 1985;35(12):1865-70.
7
[Nicergoline and platelet aggregation. A review of experimental and clinical studies (author's transl)].[尼麦角林与血小板聚集。实验与临床研究综述(作者译)]
Arzneimittelforschung. 1979;29(8a):1270-6.
8
[Therapeutic efficacy of nicergoline in ophthalmology. Fluorescence retinographic study (author's transl)].尼麦角林在眼科的治疗效果。荧光视网膜造影研究(作者译)
Arzneimittelforschung. 1979;29(8a):1311-6.
9
[Effectiveness of nicergoline in the treatment of chronic cerebrovascular insufficiency (author's transl)].尼麦角林治疗慢性脑供血不足的疗效(作者译)
Nervenarzt. 1980 Jun;51(6):368-72.
10
[Effects of nicergoline on cerebral blood flow (author's transl)].尼麦角林对脑血流量的影响(作者译)
Arzneimittelforschung. 1979;29(8a):1277-8.

引用本文的文献

1
Efficacy of nicergoline in dementia and other age associated forms of cognitive impairment.尼麦角林治疗痴呆及其他与年龄相关的认知障碍形式的疗效。
Cochrane Database Syst Rev. 2001;2001(4):CD003159. doi: 10.1002/14651858.CD003159.
2
[The effect of alpha receptor-blocking agents on inner ear function (author's transl)].α受体阻断剂对内耳功能的影响(作者译)
Arch Otorhinolaryngol. 1982;234(3):313-20. doi: 10.1007/BF00464336.