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尼麦角林在动脉高血压和慢性脑血管功能不全症状性治疗中的作用。359例观察研究(作者译)

[The role of nicergoline in the symptomatic treatment of arterial hypertension and chronic cerebrovascular insufficiency. A study on 359 observations (author's transl)].

作者信息

Dauverchain J

出版信息

Arzneimittelforschung. 1979;29(8a):1308-10.

PMID:395956
Abstract

An examination was carried out on the efficacy of 10-methoxy-1,6-diemethyl-ergoline-8 beta-methanol-(5-bromonicotinate) (nicergoline, Sermion) on the symptoms of functional side effects of arterial hypertension and chronic circulatory insufficiency as regards the psychomotoric activity and the relational activity; 359 patients suffering from crebrovascular insufficiency were included in the study. The compound was applied in a daily dose of 10 mg i. m. for 5 days and then in a daily dose of 15 mg orally for 1 month. In the entire symptom complex of cerebro-vascular insufficiency a positive effect of nicergoline could be observed; the results of all clinical criteria and their therapeutic relevance are discussed.

摘要

对10-甲氧基-1,6-二甲基-麦角灵-8β-甲醇-(5-溴烟酸酯)(尼麦角林,喜得镇)治疗动脉高血压和慢性循环功能不全功能性副作用症状的疗效进行了一项研究,涉及精神运动活动和关联活动;359例脑血管功能不全患者纳入研究。该化合物以每日10mg的剂量肌肉注射,持续5天,然后以每日15mg的剂量口服,持续1个月。在脑血管功能不全的整个症状复合体中,可以观察到尼麦角林的积极作用;讨论了所有临床标准的结果及其治疗相关性。

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