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[大鼠发热高峰期与退热期血液的区域再分布]

[Regional redistributions of blood under peaking and dropping of fever in rats].

作者信息

Kovalev O A, Sonokin A V, Batiaev M A, Sevenovostokova V I, Shetemetevskaia S K

出版信息

Biull Eksp Biol Med. 1979 Nov;88(11):533-5.

PMID:540137
Abstract

Regional redistributions of blood under height and drop of fever-heat were studied in rat experiments. Fever was induced by intravenous administration of leukocytic rabbit pyrogen as well as by intravenous injection of pyrogenal. The former factor produces more rapid and more significant temperature rise than the latter one. In all series of experiments multidimensional statistical analysis allowed one to reveal the effect conducive to a relative decrease in the blood content in the brain, myocardium, lungs, liver and to its increase in some abdominal organs, skin, muscle and bone tissues of the extremities, abdomen and pelvis. At the same time there emerged effects directed to blood redistribution mainly from organs and tissuesof the head, neck and chest to the liver.

摘要

在大鼠实验中研究了身高和发热热降情况下血液的区域再分布。通过静脉注射白细胞源性兔热原以及静脉注射热原素来诱导发热。前一种因素比后一种因素能使体温升高得更快、更显著。在所有系列实验中,多维统计分析使人们能够揭示出有利于大脑、心肌、肺、肝脏血液含量相对减少,以及有利于四肢、腹部和骨盆的某些腹部器官、皮肤、肌肉和骨骼组织血液含量增加的效应。与此同时,出现了主要从头部、颈部和胸部的器官和组织向肝脏进行血液再分布的效应。

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