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间羟异丙肾上腺素(“支气管痉挛素”)对人工诱发哮喘的抑制作用。

Inhibition of artifically-induced asthma by reproterol ('Bronchospasmin').

作者信息

Prime F J, Bianco S, Kamburoff P L

出版信息

Curr Med Res Opin. 1979;6(5):364-70. doi: 10.1185/03007997909109452.

DOI:10.1185/03007997909109452
PMID:540526
Abstract

A study was carried out in 25 patients with asthma caused by exposure to occupational antigens to investigate the effectiveness of reproterol in protecting and terminating the bronchoconstrictor response to inhaled antigens. The results of lung function tests showed that the immediate reactions to the provocation test could be reversed by reproterol given either at the time of the reaction or shortly before challenge.

摘要

对25名因接触职业性抗原而引发哮喘的患者进行了一项研究,以调查瑞普特罗在保护和终止对吸入性抗原的支气管收缩反应方面的有效性。肺功能测试结果表明,无论是在反应发生时还是在激发试验前不久给予瑞普特罗,均可逆转激发试验的即时反应。

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1
Inhibition of artifically-induced asthma by reproterol ('Bronchospasmin').间羟异丙肾上腺素(“支气管痉挛素”)对人工诱发哮喘的抑制作用。
Curr Med Res Opin. 1979;6(5):364-70. doi: 10.1185/03007997909109452.
2
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Effect of reproterol either alone or combined with disodium cromoglycate on airway responsiveness to methacholine.瑞普特罗单独使用或与色甘酸钠联合使用对气道对乙酰甲胆碱反应性的影响。
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Evaluation of reproterol's effectiveness in preventing exercise-induced bronchospasm in children.瑞普特罗预防儿童运动诱发性支气管痉挛有效性的评估。
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[Clinical evaluation of disodium cromoglycate with beta-2-agonist in therapy of patients with atopic bronchial asthma (preliminary study)].色甘酸钠与β-2-激动剂联合治疗特应性支气管哮喘患者的临床评估(初步研究)
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Efficacy of reproterol assessed by the acetylcholine provocation test.
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Bronchial and cardiovascular responses to inhaled reproterol in asthmatics: a double-blind placebo controlled dose-response study.哮喘患者对吸入瑞普特罗的支气管和心血管反应:一项双盲安慰剂对照剂量反应研究。
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Reproterol and the muscle of the trachea and bronchi: in vitro and in vivo comparative studies with various drugs used in the treatment of asthma.间羟叔丁肾上腺素与气管和支气管平滑肌:与治疗哮喘的各种药物的体外和体内比较研究
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Reproterol--A monomolecular combination of orciprenaline and theophylline: novel aspects of its mode of action in asthma.
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Inhibition of methacholine-induced bronchoconstriction with reproterol, a new beta agonist-xanthine derivative.新型β受体激动剂-黄嘌呤衍生物瑞普特罗对乙酰甲胆碱诱导的支气管收缩的抑制作用。
Ann Allergy. 1981 Apr;46(4):189-92.