运动神经元参数的一些电学测量。
Some electrical measurements of motoneuron parameters.
作者信息
Nelson P G, Lux H D
出版信息
Biophys J. 1970 Jan;10(1):55-73. doi: 10.1016/S0006-3495(70)86285-3.
Abstract
Electrical properties of the membrane of cat spinal motoneurons have been studied using pulses of current and sinusoidally varying currents applied with intracellular microelectrodes. Hyperpolarization of the motoneuron membrane produces time and voltage dependent changes in membrane resistance and E. M. F. The voltage transients produced by steps of current have been analyzed in order to determine the effective electrotonic length of the dendrites. In a sample of 16 motoneurons, the average total length of the dendrites was 1.5 times the electrotonic length constant of the dendrites. The phase relationship between applied sinusoidal currents and the resultant transmembrane voltage was studied to determine the dendritic to somatic conductance ratio, rho. In a sample of seven cells the best estimate for rho was in the range between 5 and 10.
摘要
利用细胞内微电极施加的电流脉冲和正弦变化电流，对猫脊髓运动神经元膜的电学特性进行了研究。运动神经元膜的超极化会导致膜电阻和电动势随时间和电压发生变化。对电流阶跃产生的电压瞬变进行了分析，以确定树突的有效电紧张长度。在16个运动神经元样本中，树突的平均总长度是树突电紧张长度常数的1.5倍。研究了施加的正弦电流与由此产生的跨膜电压之间的相位关系，以确定树突与体细胞的电导比ρ。在7个细胞的样本中，ρ的最佳估计值在5到10之间。
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