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酒精对红细胞生成的抑制作用。

Suppression of erythropoiesis by alcohol.

作者信息

Hourihane D O, Weir D G

出版信息

Br Med J. 1970 Jan 10;1(5688):86-9. doi: 10.1136/bmj.1.5688.86.

DOI:10.1136/bmj.1.5688.86
PMID:5411451
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1699174/
Abstract

Serial measurements in alcoholic subjects showed a profound fall of serum iron for three days after withdrawal of alcohol and a reversion of abnormal accumulation of erythroblastic haemosiderin to normal. These findings suggest an interference in normal haem synthesis, most probably by a direct effect.

摘要

对酒精性肝病患者的系列检测显示,戒酒三天后血清铁显著下降,成红细胞性含铁血黄素异常蓄积恢复正常。这些发现提示正常血红素合成受到干扰,很可能是直接作用所致。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/731c/1699174/97bfec1a850e/brmedj02269-0050-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/731c/1699174/a539607566fa/brmedj02269-0049-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/731c/1699174/97bfec1a850e/brmedj02269-0050-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/731c/1699174/a539607566fa/brmedj02269-0049-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/731c/1699174/97bfec1a850e/brmedj02269-0050-a.jpg

相似文献

1
Suppression of erythropoiesis by alcohol.酒精对红细胞生成的抑制作用。
Br Med J. 1970 Jan 10;1(5688):86-9. doi: 10.1136/bmj.1.5688.86.
2
The role of inhibitors of heme synthesis and bone marrow erythroid colony forming cells in the mechanism of anemia of renal insufficiency.血红素合成抑制剂和骨髓红系集落形成细胞在肾功能不全贫血机制中的作用。
Proc Clin Dial Transplant Forum. 1974(4):141-6.
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4
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Scand J Haematol. 1973;10(5):321-6. doi: 10.1111/j.1600-0609.1973.tb00079.x.
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Pure red-cell aplasia.纯红细胞再生障碍性贫血
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6
Erythropoiesis in chronic renal disease.慢性肾病中的红细胞生成
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Bone marrow erythropoiesis in the anemia of infection, inflammation, and malignancy.感染、炎症和恶性肿瘤所致贫血中的骨髓红细胞生成
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8
[Disorders of erythropoiesis and the immune system caused by alcohol. 1. Erythropoiesis].
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引用本文的文献

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Novel Insights into Alcoholic Liver Disease: Iron Overload, Iron Sensing and Hemolysis.酒精性肝病的新见解:铁过载、铁感应与溶血
J Transl Int Med. 2022 Jul 10;10(2):92-124. doi: 10.2478/jtim-2021-0056. eCollection 2022 Jun.
2
Sun, iron, alcohol and intrinsic liver disease: a recipe for failure.阳光、铁、酒精与内在肝脏疾病:失败的组合。
BMJ Case Rep. 2013 Jul 2;2013:bcr2013200158. doi: 10.1136/bcr-2013-200158.
3
[Alcohol induced changes in hemopoiesis (author's transl)].酒精引起的造血变化(作者译)

本文引用的文献

1
The anemia of liver disease: observations on its mechanism.肝病性贫血:其机制的观察
J Clin Invest. 1955 Mar;34(3):390-404. doi: 10.1172/JCI103087.
2
PYRIDOXINE-RESPONSIVE ANEMIA: ANALYSIS OF 62 CASES.吡哆醇反应性贫血:62例病例分析。
Adv Intern Med. 1964;12:103-74.
3
THE MECHANISM OF ANAEMIA IN CHRONIC LIVER DISEASE.慢性肝病贫血的机制
Klin Wochenschr. 1981 Dec 1;59(23):1303-12. doi: 10.1007/BF01711180.
4
The pathogenesis of folic acid deficiency in man.人类叶酸缺乏的发病机制。
Ir J Med Sci. 1974 Jan;143(1):3-20. doi: 10.1007/BF03004735.
5
Alcohol and the blood.酒精与血液
Br Med J. 1978 Jun 10;1(6126):1504-5.
6
[Alcohol-related disturbances in haematopoiesis (author's transl)].造血过程中与酒精相关的紊乱(作者译)
Klin Wochenschr. 1978 Mar 15;56(6):259-65. doi: 10.1007/BF01489170.
Q J Med. 1965 Jan;34:33-64.
4
SUPPRESSION HEMATOPOIESIS BY ETHANOL.乙醇对造血的抑制作用。
J Clin Invest. 1964 Nov;43(11):2048-62. doi: 10.1172/JCI105079.
5
ABNORMAL LEUKOCYTE RESPONSE IN ALCOHOLISM.酒精中毒时的异常白细胞反应
Ann Intern Med. 1963 Dec;59:865-77. doi: 10.7326/0003-4819-59-6-865.
6
WINE AS SOURCE OF IRON IN HAEMOCHROMATOSIS.血色沉着病中葡萄酒作为铁的来源
Nature. 1963 Aug 31;199:922. doi: 10.1038/199922a0.
7
Effect of chloramphenicol on erythropoiesis.氯霉素对红细胞生成的影响。
J Lab Clin Med. 1961 Feb;57:247-56.
8
Changes in iron metabolism in early chloramphenicol toxicity.早期氯霉素毒性中铁代谢的变化。
J Clin Invest. 1958 Sep;37(9):1286-92. doi: 10.1172/JCI103716.
9
A new method for the determination of serum iron-binding capacity. I.
J Lab Clin Med. 1956 Aug;48(2):274-9.
10
Value of serum iron levels in assessing effect of haematinics in the macrocytic anaemias.血清铁水平在评估补血药对巨细胞性贫血疗效中的价值。
Br Med J. 1955 Feb 12;1(4910):383-5. doi: 10.1136/bmj.1.4910.383.