Corbett M, Seifert M H, Hacking C, Webb S
Br Med J. 1970 Jan 3;1(5687):24-5. doi: 10.1136/bmj.1.5687.24.
One of three preparations-silicone oil, hydrocortisone acetate, and hydrocortisone acetate plus saline-was injected into 22 osteoarthritic and 49 rheumatoid knees. Silicone injected into stiff, dry, grating knees which were the site of chronic arthritis did not promote better movement than did hydrocortisone alone. Hydrocortisone plus saline, however, appeared to be more effective than silicone or hydrocortisone alone in increasing movement in rheumatoid knees. The maximum increase in movement was found to occur three weeks after each of the three different injection preparations.
将三种制剂（硅油、醋酸氢化可的松、醋酸氢化可的松加生理盐水）之一注入22个骨关节炎膝关节和49个类风湿性膝关节。注入慢性关节炎部位僵硬、干燥、有摩擦感的膝关节的硅油，并不比单独使用氢化可的松更能促进关节更好地活动。然而，在增加类风湿性膝关节的活动度方面，醋酸氢化可的松加生理盐水似乎比单独使用硅油或氢化可的松更有效。发现三种不同注射制剂中的每一种注射后三周，关节活动度增加最大。
