Cruse P J
Can Med Assoc J. 1970 Feb 14;102(3):251-8.
With the help of a surgical nurse and using data-processing techniques, a prospective clinical study was conducted to determine the wound infection rate in two hospitals in Calgary. The overall sepsis rate was 5.2% and the clean wound rate 3.5%. The latter is the more meaningful figure as it allows for comparison between hospitals, specialties and individuals and is a good guide for hospital morbidity reviews. The groundwork for succeeding wound infection is laid in the operating theatre, and it is believed that wound infection would be reduced more by attention to Halsted's principles than by more rigid aseptic techniques. It is estimated that wound sepsis costs the Province of Alberta 1.5 million dollars per year for hospitalization alone. This amounts to roughly $1 per person per year. The annual cost of a prospective study such as the present one is approximately $7000. This is equivalent to the cost of hospitalizing 24 patients with infected wounds for one week (at $300 per week). One dividend of a prospective study is an associated reduction in infection rate. This reduction more than pays for the cost of the program.
在一名外科护士的协助下,运用数据处理技术,在卡尔加里的两家医院开展了一项前瞻性临床研究,以确定伤口感染率。总体败血症发生率为5.2%,清洁伤口发生率为3.5%。后者是更具意义的数据,因为它有助于医院之间、不同专科以及个体之间进行比较,并且是医院发病率评估的良好指标。伤口感染的根源在手术室,人们认为,相较于更严格的无菌技术,关注霍尔斯特德原则能更有效地降低伤口感染率。据估计,仅住院一项,伤口败血症每年就让艾伯塔省花费150万美元。这大约相当于每人每年1美元。像本研究这样的前瞻性研究每年的成本约为7000美元。这相当于24名伤口感染患者住院一周的费用(每周300美元)。前瞻性研究的一个好处是感染率会相应降低。这种降低带来的收益超过了该项目的成本。