• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

相似文献

1
A comparison of the heterogeneous nuclear RNA of HeLa cells in different periods of the cell growth cycle.对海拉细胞在细胞生长周期不同阶段的不均一核RNA的比较。
J Cell Biol. 1970 Mar;44(3):476-83. doi: 10.1083/jcb.44.3.476.
2
A comparison between heterogeneous nuclear RNA and polysomal messenger RNA in HeLa cells by RNA-DNA hybridization.通过RNA-DNA杂交对海拉细胞中的不均一核RNA和多聚核糖体信使RNA进行比较。
J Cell Biol. 1970 Mar;44(3):467-75. doi: 10.1083/jcb.44.3.467.
3
Messenger and heterogeneous nuclear RNA in HeLa cells: differential inhibition by cordycepin.HeLa细胞中的信使核糖核酸和不均一核核糖核酸：虫草素的差异抑制作用
Proc Natl Acad Sci U S A. 1970 Dec;67(4):1878-85. doi: 10.1073/pnas.67.4.1878.
4
Reversible inhibition of ribosomal RNA synthesis in HeLa by lucanthone (Miracil D) with continued synthesis of DNA-like RNA.路噻酮（密安宁D）对海拉细胞核糖体RNA合成的可逆性抑制以及类DNA-RNA的持续合成。
J Cell Physiol. 1969 Dec;74(3):283-94. doi: 10.1002/jcp.1040740308.
5
Mitochondrial origin of membrane-associated heterogeneous RNA in HeLa cells.HeLa细胞中膜相关异质性RNA的线粒体起源
Proc Natl Acad Sci U S A. 1968 Sep;61(1):261-8. doi: 10.1073/pnas.61.1.261.
6
Double-stranded regions in heterogeneous nuclear RNA from Hela cells.来自海拉细胞的不均一核RNA中的双链区域。
Proc Natl Acad Sci U S A. 1972 Sep;69(9):2537-41. doi: 10.1073/pnas.69.9.2537.
7
The small molecular weight monodisperse nuclear RNA's in mitotic cells.有丝分裂细胞中的小分子单分散核RNA
Biochim Biophys Acta. 1971 Mar 11;232(2):306-13. doi: 10.1016/0005-2787(71)90583-1.
8
Preferential methylation of regulatory genes in HeLa cells.HeLa细胞中调控基因的优先甲基化
FEBS Lett. 1974 Aug 25;44(2):121-6. doi: 10.1016/0014-5793(74)80708-8.
9
The distribution of rapidly hybridizing RNA sequences in heterogeneous nuclear RNA and mRNA from HeLa cells.HeLa细胞异质性核RNA和mRNA中快速杂交RNA序列的分布
J Cell Physiol. 1970 Dec;76(3):349-56. doi: 10.1002/jcp.1040760312.
10
Ribonucleic acid synthesis in the cell cycle of L5178Y mouse leukemic cells. Time of replication of the DNA template of rapidly labeled hybridizable RNA.
Exp Cell Res. 1971 Jul;67(1):90-6. doi: 10.1016/0014-4827(71)90624-0.

引用本文的文献

1
Long non-coding RNAs: roles in cellular stress responses and epigenetic mechanisms regulating chromatin.长非编码 RNA：在细胞应激反应和调节染色质的表观遗传机制中的作用。
Nucleus. 2024 Dec;15(1):2350180. doi: 10.1080/19491034.2024.2350180. Epub 2024 May 22.
2
Nascent RNA scaffolds contribute to chromosome territory architecture and counter chromatin compaction.初生 RNA 支架有助于染色体域结构并对抗染色质的紧缩。
Mol Cell. 2021 Sep 2;81(17):3509-3525.e5. doi: 10.1016/j.molcel.2021.07.004. Epub 2021 Jul 27.
3
RNA synthesis in HeLa cells. Pattern in hypertonic medium and its similarity to synthesis during G2-prophase.海拉细胞中的RNA合成。高渗培养基中的模式及其与G2期前期合成的相似性。
J Cell Biol. 1970 Dec;47(3):734-44. doi: 10.1083/jcb.47.3.734.
4
A comparison between heterogeneous nuclear RNA and polysomal messenger RNA in HeLa cells by RNA-DNA hybridization.通过RNA-DNA杂交对海拉细胞中的不均一核RNA和多聚核糖体信使RNA进行比较。
J Cell Biol. 1970 Mar;44(3):467-75. doi: 10.1083/jcb.44.3.467.
5
Topology of repeated sequences: relationship of nuclear RNA to the repeated sequences of the main and satellite DNA in mouse plasmocytoma cells.重复序列的拓扑结构：小鼠浆细胞瘤细胞核RNA与主DNA和卫星DNA重复序列的关系
Proc Natl Acad Sci U S A. 1974 Sep;71(9):3664-8. doi: 10.1073/pnas.71.9.3664.

本文引用的文献

1
The cytoplasmic synthesis of histones in hela cells and its temporal relationship to DNA replication.海拉细胞中组蛋白的细胞质合成及其与DNA复制的时间关系。
Proc Natl Acad Sci U S A. 1967 Feb;57(2):409-16. doi: 10.1073/pnas.57.2.409.
2
POLYRIBOSOMES IN NORMAL AND POLIOVIRUS-INFECTED HELA CELLS AND THEIR RELATIONSHIP TO MESSENGER-RNA.正常及脊髓灰质炎病毒感染的海拉细胞中的多核糖体及其与信使核糖核酸的关系
Proc Natl Acad Sci U S A. 1963 May;49(5):654-62. doi: 10.1073/pnas.49.5.654.
3
Methylation of 45 s ribosomal RNA precursor in HeLa cells.HeLa细胞中45s核糖体RNA前体的甲基化
J Mol Biol. 1967 Jan 28;23(2):149-61. doi: 10.1016/s0022-2836(67)80023-8.
4
Giant-size rapidly labeled nuclear ribonucleic acid and cytoplasmic messenger ribonucleic acid in immature duck erythrocytes.未成熟鸭红细胞中的巨大快速标记核糖核酸和细胞质信使核糖核酸
J Mol Biol. 1966 Sep;20(1):145-82. doi: 10.1016/0022-2836(66)90123-9.
5
Rapidly labeled HeLa cell nuclear RNA. II. Base composition and cellular localization of a heterogeneous RNA fraction.快速标记的海拉细胞核RNA。II. 一种不均一RNA组分的碱基组成和细胞定位
J Mol Biol. 1966 Aug;19(2):362-72. doi: 10.1016/s0022-2836(66)80010-4.
6
RNA metabolism in the HeLa cell nucleus.海拉细胞核中的RNA代谢
J Mol Biol. 1966 May;17(1):117-30. doi: 10.1016/s0022-2836(66)80098-0.
7
Synthesis of ribosomal RNA in synchronized HeLa cells.同步化的海拉细胞中核糖体RNA的合成
Nature. 1965 Oct 30;208(5009):464-6. doi: 10.1038/208464a0.
8
Methylation of nucleic acids in HeLa cells.HeLa细胞中核酸的甲基化
Biochem Biophys Res Commun. 1965 Jul 26;20(3):298-302. doi: 10.1016/0006-291x(65)90363-3.
9
[Remarks on polycistron messenger RNA's in animal cells].[关于动物细胞中多顺反子信使核糖核酸的论述]
Bull Soc Chim Biol (Paris). 1965;47(8):1697-713.
10
Cyclic changes in enzyme activity in synchronized mammalian cell cultures.同步化哺乳动物细胞培养中酶活性的周期性变化。
Science. 1968 Feb 9;159(3815):634-6. doi: 10.1126/science.159.3815.634.

对海拉细胞在细胞生长周期不同阶段的不均一核RNA的比较。

A comparison of the heterogeneous nuclear RNA of HeLa cells in different periods of the cell growth cycle.

作者信息

Pagoulatos G N, Darnell J E

出版信息

J Cell Biol. 1970 Mar;44(3):476-83. doi: 10.1083/jcb.44.3.476.

DOI:10.1083/jcb.44.3.476
PMID:5415232
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2107977/
Abstract

HeLa cells synthesize heterogeneous nuclear RNA (HnRNA) in the G(1), S, and G(2) portions of the cell cycle. HnRNA prepared from these various periods was compared by RNA-DNA hybridization experiments. The results indicated that some of the HnRNA molecules were equivalent at all times in the cell cycle, but limitations in the sensitivity of the hydridization reactions, as well as in the spectrum of hybridizing molecules, restrict the conclusions that can be drawn from these comparisons.

摘要

海拉细胞在细胞周期的G1期、S期和G2期合成不均一核RNA（HnRNA）。通过RNA-DNA杂交实验对从这些不同时期制备的HnRNA进行了比较。结果表明，某些HnRNA分子在细胞周期的所有时间都是等同的，但是杂交反应敏感性以及杂交分子谱方面的局限性，限制了从这些比较中得出的结论。