[人类颊黏膜上皮细胞Y染色质的研究]
[Study of Y-chromatin in the buccal epithelium of man].
作者信息
Zakharov A M, Kulikov R I
出版信息
Arkh Anat Gistol Embriol. 1975 May;68(5):18-23.
PMID:54155
Abstract
Investigation was carried on by fluorescent-microscopic technique, smears of buccal epithelium being stained with acrichinium-mustard gas. The extent, form, location in a nucleus and the frequency of Y-chromatin in human buccal smears were studied. In medico-genetic practice this method is employed for initial determination of chromosome sex in disease associated with anomalies of sex chromosomes.
摘要
采用荧光显微镜技术进行研究，用吖啶黄-芥子气对颊黏膜上皮涂片进行染色。研究了人类颊黏膜涂片中Y染色质的范围、形态、在细胞核中的位置及出现频率。在医学遗传学实践中，该方法用于初步确定与性染色体异常相关疾病的染色体性别。
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