成年负鼠（弗吉尼亚负鼠）对噬菌体f2的免疫反应。
The immune response of adult opossums (Didelphis virginiana) to the bacteriophage f2.
作者信息
Rowlands D T
出版信息
Immunology. 1970 Feb;18(2):149-55.
Abstract
Humoral immunity to the bacteriophage f2 was studied in adult opossums () and their responses were compared to those in New Zealand White rabbits. Antibodies were found in the serum of opossums 7 days after the subcutaneous injection of the antigen and peak antibody responses were observed between 10 and 21 days after immunization. A second injection of antigen resulted in increased antibody activity. In either case the level of serum antibody reached in opossums was less than that in rabbits. More striking, however, was the relatively slow conversion from γM to γG antibodies in opossums. The course of the immune response in adult opossums was more nearly like that of cold-blooded vertebrates than that of eutherian mammals.
摘要
研究了成年负鼠对噬菌体f2的体液免疫，并将它们的反应与新西兰白兔的反应进行了比较。皮下注射抗原7天后，在负鼠血清中发现了抗体，免疫后10至21天观察到抗体反应达到峰值。第二次注射抗原导致抗体活性增加。在这两种情况下，负鼠血清抗体水平均低于兔子。然而，更引人注目的是，负鼠中从γM抗体到γG抗体的转换相对较慢。成年负鼠的免疫反应过程更类似于冷血脊椎动物，而不是真兽类哺乳动物。
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