Benrey J, Gillette P C, Nasrallah A T, Hallman G L
Circulation. 1976 Feb;53(2):245-8. doi: 10.1161/01.cir.53.2.245.
Twenty-four patients in the pediatric age range who underwent implantation of a cardiac pacemaker for treatment of complete atrioventricular (A-V) block were followed for an average of five years (range 1-12 years). The etiology of the A-V block was surgical in 13 cases, congenital in nine, and acquired in two. Twenty patients had symptoms of cerebrovascular insufficiency and four had congestive heart failure. To date, 18 of the 24 patients studied are alive and well. Death occurred in six patients, five of whom had complex congenital heart defects, and one of whom had Refsum's disease. Death probably was caused by complete heart block despite pacemaker treatment in four patients, and congestive heart failure in two. In 18 of the 24 children with disabling complete A-V block, pacemaker therapy provided relief of symptoms and prolonged life.
24名接受心脏起搏器植入术以治疗完全性房室传导阻滞的儿童患者，平均随访了5年（范围为1至12年）。房室传导阻滞的病因在13例中是手术性的，9例是先天性的，2例是后天获得性的。20例有脑血管供血不足症状，4例有充血性心力衰竭。迄今为止，所研究的24例患者中有18例存活且状况良好。6例患者死亡，其中5例有复杂的先天性心脏缺陷，1例患有Refsum病。4例患者死亡可能是由于尽管进行了起搏器治疗仍发生完全性心脏传导阻滞，2例是由于充血性心力衰竭。在24例患有致残性完全性房室传导阻滞的儿童中，有18例通过起搏器治疗缓解了症状并延长了生命。
