Howard C J, Brownlie J
Res Vet Sci. 1979 Nov;27(3):388-9.
Bovine IgG1, IgG2, and IgM initiated haemolysis by bovine complement. With guinea pig complement bovine IgG1 and IgM appeared effective, but bovine IgG2 was much less effective. Single radial haemolysis systems using guinea pig complement to measure bovine antibody are likely to detect predominantly IgG1 and IgM. However, in vivo IgG2 should activate bovine complement.
牛IgG1、IgG2和IgM可通过牛补体引发溶血。对于豚鼠补体，牛IgG1和IgM似乎有作用，但牛IgG2的作用要小得多。使用豚鼠补体的单向辐射溶血系统来检测牛抗体，可能主要检测到的是IgG1和IgM。然而，在体内IgG2应该能激活牛补体。
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