Thomson C G, Cleator I G, Sircus W
Gut. 1970 May;11(5):409-19. doi: 10.1136/gut.11.5.409.
Reported here are the assay results, using the anaesthetized rat preparation of Lai (1964), of plasma from patients known or suspected to have peptide-secreting adenomata and these are compared with assays carried out on plasma from patients whose clinical history excluded such pathology. It is suggested that these demonstrate that this technique is of diagnostic value in this condition and that it has practical advantages over other bio-assay methods currently available and physiological advantages over immunological methods. It may well be that identification of the presence of tumour in these patients may first be made by immunological techniques to be followed by functional identification using a bioassay procedure such as is described here.
本文报告了使用赖（1964年）的麻醉大鼠制备方法，对已知或疑似患有肽分泌腺瘤患者的血浆进行的检测结果，并将其与对临床病史排除此类病变的患者血浆进行的检测结果进行了比较。结果表明，这些结果证明该技术在这种情况下具有诊断价值，并且与目前可用的其他生物检测方法相比具有实际优势，与免疫方法相比具有生理优势。很可能这些患者中肿瘤的存在首先通过免疫技术进行鉴定，随后使用本文所述的生物检测程序进行功能鉴定。
