Lowe C R, Campbell H, Khosla T
Br J Ind Med. 1970 Apr;27(2):121-9. doi: 10.1136/oem.27.2.121.
121-129. This is the third in a series of papers presenting the results of an epidemiological study of respiratory symptomatology and lung function among men employed in two integrated steel works in South Wales. In this paper measurements of atmospheric pollution are related to respiratory symptoms and ventilatory capacity among 10 449 men who spent the greater part of their working hours in one or other of 114 defined working areas. The problem has been explored in three different ways. In the first, each man was assigned the mean value of sulphur dioxide and respirable dust for the area in which he was working and this was related to his ventilatory capacity (FEV), age, smoking habits, and the number of years he had spent in his present department. In the second, the 114 working areas were divided into four sub-groups, according to defined levels of atmospheric pollution, and the prevalence of chronic bronchitis and mean FEV in the four sub-groups was examined. In the third way, the mean atmospheric pollution levels in each of the 114 areas were related to the prevalence of bronchitis and to the mean FEV, age, and smoking habits in those areas. The analysis demonstrates very clearly the over-riding importance of cigarette smoking in the aetiology of chronic bronchitis, but, so far as the main purpose of the survey is concerned, it is concluded that, if there is any relation between respiratory disability and atmospheric pollution in the two steel works, it is so slight that none of the three approaches to the problem was sensitive enough to detect it. The implications of this are discussed in the light of the levels of pollution that were recorded in and around the two works.
121 - 129。这是一系列论文中的第三篇，该系列论文呈现了对南威尔士两家综合钢铁厂男性员工的呼吸道症状和肺功能进行流行病学研究的结果。在本文中，对大气污染的测量结果与10449名男性的呼吸道症状和通气能力相关，这些男性大部分工作时间在114个明确界定的工作区域中的一个或另一个区域度过。这个问题通过三种不同方式进行了探究。第一种方式是，为每个男性分配其工作区域的二氧化硫和可吸入粉尘的平均值，并将其与他的通气能力（第一秒用力呼气量）、年龄、吸烟习惯以及他在当前部门工作的年数相关联。第二种方式是，根据大气污染的既定水平，将114个工作区域分为四个亚组，并检查这四个亚组中慢性支气管炎的患病率和平均第一秒用力呼气量。第三种方式是，将114个区域中每个区域的平均大气污染水平与支气管炎的患病率以及这些区域的平均第一秒用力呼气量、年龄和吸烟习惯相关联。分析非常清楚地表明了吸烟在慢性支气管炎病因学中的首要重要性，但是，就该调查的主要目的而言，得出的结论是，如果两家钢铁厂中呼吸功能障碍与大气污染之间存在任何关联，这种关联非常轻微，以至于解决该问题的三种方法中没有一种足够灵敏能够检测到它。根据两家工厂及其周边记录的污染水平对这一结果的影响进行了讨论。
