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反应性低血糖症中肠道胰高血糖素释放增加。

Increased release of gut glucagon in reactive hypoglycaemia.

作者信息

Rehfeld J F, Heding L G

出版信息

Br Med J. 1970 Jun 20;2(5711):706-7. doi: 10.1136/bmj.2.5711.706.

Abstract

A patient with reactive hypoglycaemia showed hypersecretion of insulin in response to enteral beta-cell stimulation. Increased levels of gut glucagon-like immunoreactivity in serum were demonstrated by use of specific antisera. Other measurable hormones influencing carbohydrate metabolism were within normal limits. It is suggested that gut glucagon-like immunoreactivity may be of pathogenetic significance in reactive hypoglycaemia.

摘要

一名反应性低血糖患者在接受肠内β细胞刺激后出现胰岛素分泌过多。通过使用特异性抗血清,证实血清中肠胰高血糖素样免疫反应性水平升高。其他影响碳水化合物代谢的可测量激素均在正常范围内。提示肠胰高血糖素样免疫反应性可能在反应性低血糖的发病机制中具有重要意义。

相似文献

4
Increased gut glucagon release as pathogenetic factor in reactive hypoglycaemia?
Lancet. 1973 Jan 20;1(7795):116-8. doi: 10.1016/s0140-6736(73)90193-1.
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Gut glucagon and reactive hypoglycaemia.肠道胰高血糖素与反应性低血糖症。
Lancet. 1973 Jan 27;1(7796):202. doi: 10.1016/s0140-6736(73)90030-5.

引用本文的文献

本文引用的文献

1
Spontaneous hypoglycemia.
Am J Med. 1955 Sep;19(3):460-78. doi: 10.1016/0002-9343(55)90130-3.
5
New ideas concerning the physiologic roles of glucagon.
Am J Med Sci. 1968 May;255:273-6. doi: 10.1097/00000441-196805000-00001.
7
Pathophysiology of post-gastrectomy hypoglycaemia.胃切除术后低血糖的病理生理学
Br Med J. 1969 Nov 1;4(5678):257-9. doi: 10.1136/bmj.4.5678.257.
8
Intestinal factors in the control of insulin secretion.胰岛素分泌调控中的肠道因素。
J Clin Endocrinol Metab. 1965 Oct;25(10):1317-24. doi: 10.1210/jcem-25-10-1317.

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