Amabis J M, Cabral D
Science. 1970 Aug 14;169(3946):692-4. doi: 10.1126/science.169.3946.692.
In the giant polytene chromosomes, gene amplification is made visible by formation of DNA puffs, and gene transcription is made visible by formation of RNA puffs. Ligation of the anterior portion of the larva at the end of the fourth larval instar inhibited the formation of the DNA puffs that normally develop at this stage and caused regression of RNA puffs.
在巨大的多线染色体中,基因扩增通过DNA泡的形成而可见,基因转录通过RNA泡的形成而可见。在第四龄幼虫末期结扎幼虫前部,抑制了在此阶段正常发育的DNA泡的形成,并导致RNA泡消退。