Henney C S, Waldman R H
Science. 1970 Aug 14;169(3946):696-7. doi: 10.1126/science.169.3946.696.
Cell-mediated immunity, as evidenced by inhibition of macrophage migration in the presence of antigen, was associated with lymphocytes obtained from the respiratory tract of guinea pigs immunized by dinitrophenylated human immunoglobulin G in nose drops, but not from those immunized parenterally. However, splenic lymphocytes from parenterally immunized animals inhibited macrophage migration while those from locally immunized animals did not.
细胞介导的免疫，如在抗原存在下巨噬细胞迁移受到抑制所证明的，与从经滴鼻给予二硝基苯基化人免疫球蛋白G免疫的豚鼠呼吸道获得的淋巴细胞有关，但与经胃肠外免疫的豚鼠呼吸道获得的淋巴细胞无关。然而，经胃肠外免疫的动物的脾淋巴细胞抑制巨噬细胞迁移，而经局部免疫的动物的脾淋巴细胞则不抑制。
