Hofstetter R, Schmidt H P, Krebs W, Lang D, von Bernuth G
Z Geburtshilfe Perinatol. 1979 Oct;183(5):335-8.
Two groups each consisting of twelve healthy students received Fenoterol (0,03 microgram/kg/min) alone or in combination with Verapamil (1,2 micrograms/kg/min) intravenously. In both groups, heart rate, arterial blood pressure amplitude and echocardiographically determined left ventricular contractility parameters increased significantly and equally. These results suggest that Verapamil does not counteract the positive chronotropic and inotropic effect of Fenoterol.
两组各由十二名健康学生组成,他们分别静脉注射了单独的非诺特罗(0.03微克/千克/分钟)或与维拉帕米联合使用(1.2微克/千克/分钟)。在两组中,心率、动脉血压幅度和超声心动图测定的左心室收缩参数均显著且同等程度地增加。这些结果表明,维拉帕米不会抵消非诺特罗的正性变时性和变力性作用。