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豆科木蓝提取物中的致畸因子——豆科木蓝碱导致腭裂。

Indospicine--the teratogenic factor from Indigofera spicata extract causing cleft palate.

作者信息

Pearn J H, Hegarty M P

出版信息

Br J Exp Pathol. 1970 Feb;51(1):34-6.

PMID:5434443
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2072212/
Abstract

The amidine-containing amino acid, indospicine, has been shown to be the teratogenic principle in the crude extract which causes cleft palate in foetal rats exposed to it on Day 13 of gestation. Possible implications of its chemical structure are discussed.

摘要

含脒基氨基酸吲哚西平已被证明是粗提物中的致畸成分，该粗提物会使在妊娠第13天接触它的胎鼠出现腭裂。文中讨论了其化学结构可能产生的影响。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/34e1/2072212/26e495ed8221/brjexppathol00427-0054-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/34e1/2072212/26e495ed8221/brjexppathol00427-0054-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/34e1/2072212/26e495ed8221/brjexppathol00427-0054-a.jpg

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