Pearn J H, Hegarty M P
Br J Exp Pathol. 1970 Feb;51(1):34-6.
The amidine-containing amino acid, indospicine, has been shown to be the teratogenic principle in the crude extract which causes cleft palate in foetal rats exposed to it on Day 13 of gestation. Possible implications of its chemical structure are discussed.
含脒基氨基酸吲哚西平已被证明是粗提物中的致畸成分,该粗提物会使在妊娠第13天接触它的胎鼠出现腭裂。文中讨论了其化学结构可能产生的影响。