Bold M, Menzies I S, Walker G
J Clin Pathol. 1970 Feb;23(1):85-9. doi: 10.1136/jcp.23.1.85.
The approximate concentration of urea in a single, unmeasured drop of blood may be estimated with an Azostix strip in a little over a minute, without the use of laboratory equipment. The test has been assessed by comparing 488 strip readings made by two observers on 331 specimens of blood from patients with plasma urea concentrations determined by the Auto-Analyzer diacetyl monoxime method. Observations were also made on inter- and intra-observer reading differences, on the effect of the period of contact of blood with the reagent zone of the strip and on the effect of different types of illumination. Difficulties with visual colour matching inevitably limit the performance of this type of test. Azostix strips cannot replace laboratory methods, but, provided their limitations are appreciated, and proper technique is observed, they should provide a screening test for azotaemia when laboratory facilities are not readily available. Their place in hospitals would seem to be confined to emergency use as a screening test for severe azotaemia. In general and domiciliary practice they should provide a convenient screening test for azotaemia provided that readings greater than ;20 mg/100 ml' are taken as an indication for further investigation.
使用Azostix试纸条，在一分钟多一点的时间内，无需使用实验室设备，就可以估算出一滴未经检测的血液中尿素的大致浓度。通过比较两位观察者对331份患者血液样本所做的488次试纸条读数与用自动分析仪二乙酰一肟法测定的血浆尿素浓度，对该测试进行了评估。还观察了观察者之间和观察者内部读数的差异、血液与试纸条试剂区接触时间的影响以及不同类型光照的影响。视觉颜色匹配的困难不可避免地限制了这类测试的性能。Azostix试纸条不能取代实验室方法，但是，如果认识到它们的局限性并遵循正确的技术，在实验室设施不易获得时，它们应该能为氮血症提供一种筛查测试。它们在医院的用途似乎仅限于作为严重氮血症的紧急筛查测试。在一般和家庭医疗实践中，只要将读数大于“20mg/100ml”作为进一步检查的指征，它们应该能为氮血症提供一种方便的筛查测试。
