Dajani A S, Gray E D, Wannamaker L W
J Exp Med. 1970 May 1;131(5):1004-15. doi: 10.1084/jem.131.5.1004.
A bactericidal substance previously isolated from phage type 71 Slaphylococcus aureus has been further identified and characterized. Staphylococci belonging to phage type 71 produce the substance in higher titers than staphylococci lysed by other phages in group II in addition to phage 71. Other staphylococci do not produce the bactericidal substance. The bactericidal substance shares several of the properties of bacteriocins but differs from this group of antibiotic substances in some respects. A combination of ammonium sulfate fractionation and gel filtration on a Sephadex G-100 column resulted in considerable degree of purification of the bactericidal substance. The substance is a previously unrecognized product of S. aureus and is distinct from other extracellular products of this organism.
一种先前从71型噬菌体金黄色葡萄球菌中分离出的杀菌物质已得到进一步鉴定和表征。属于71型噬菌体的葡萄球菌产生该物质的效价比除71型噬菌体外的II组其他噬菌体裂解的葡萄球菌更高。其他葡萄球菌不产生这种杀菌物质。该杀菌物质具有细菌素的若干特性，但在某些方面与这类抗生素物质不同。硫酸铵分级分离和在Sephadex G - 100柱上进行凝胶过滤相结合，使杀菌物质得到了相当程度的纯化。该物质是金黄色葡萄球菌一种先前未被识别的产物，且与该生物体的其他细胞外产物不同。
