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金黄色葡萄球菌杀菌物质对 A 组链球菌的作用 II. 结构改变。

Effect of Bactericidal Substance from Staphylococcus aureus on Group A Streptococci II. Structural Alterations.

机构信息

Department of Pediatrics, University of Minnesota College of Medical Sciences, Minneapolis, Minnesota 55455.

出版信息

Infect Immun. 1970 May;1(5):491-8. doi: 10.1128/iai.1.5.491-498.1970.

DOI:10.1128/iai.1.5.491-498.1970
PMID:16557764
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC415930/
Abstract

Ultrastructural alterations brought about by treatment of a beta-hemolytic streptococcus with a bactericidal substance from Staphylococcus aureus are described and illustrated. The substance causes an early condensation of nucleoid deoxyribonucleic acid (DNA) and a partial loss of ribosomes. These changes are followed by a dissolution of the cell contents resulting in bacterial "ghosts" composed of empty cell wall and capsule. These morphological findings correlate with known biochemical effects of the bactericidal substance on ribonucleic acid degradation and cessation of DNA and protein synthesis.

摘要

本文描述并图示了用金黄色葡萄球菌的杀菌物质处理β-溶血性链球菌引起的超微结构改变。该物质导致核体脱氧核糖核酸（DNA）早期凝聚和核糖体部分丢失。这些变化之后，细胞内容物溶解，导致由空细胞壁和荚膜组成的细菌“幽灵”。这些形态学发现与杀菌物质对核糖核酸降解以及 DNA 和蛋白质合成停止的已知生化效应相吻合。

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本文引用的文献

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Effect of Bactericidal Substance from Staphylococcus aureus on Group A Streptococci I. Biochemical Alterations.金黄色葡萄球菌杀菌物质对 A 组链球菌的作用 I. 生化改变。
Infect Immun. 1970 May;1(5):485-90. doi: 10.1128/iai.1.5.485-490.1970.
2
THE BACTERIOCINS.细菌素
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3
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