Evans J M, Rosen M, MacCarthy J, Hogg M I
Lancet. 1976 Jan 3;1(7949):17-8. doi: 10.1016/s0140-6736(76)92910-x.
The intermittent intravenous administration of narcotic analgesics had advantages over intramuscular administration, but is often impracticable. The design of a prototype apparatus is described, from which analgesic, pethidine, can be self-administered intravenously during labour. The apparatus consists of a syringe pump and control system from which the patient can demand an increment of analgesic. The minimum interval between increments and the dose of the increment are preset. A demand for analgesia is only successful when the patient passes a reaction-time test, subsequently modified. The apparatus has been used by forty-two mothers in labour. The mean total dose self-administered (2.2 mg/kg) was well within the prescribed limits, suggesting that mothers regulated their demand. The apparatus appears acceptable and safe in labour. The apparatus will probably be of value in comparative studies of analgesics.
间歇性静脉注射麻醉性镇痛药比肌肉注射有优势，但通常不实用。本文描述了一种原型装置的设计，产妇在分娩过程中可通过该装置自行静脉注射镇痛药哌替啶。该装置由一个注射泵和控制系统组成，患者可通过该系统要求增加镇痛药剂量。增量之间的最短间隔和增量剂量均已预设。只有当患者通过一项经过改进的反应时间测试后，镇痛需求才会成功。该装置已被42位分娩产妇使用。自行注射的平均总剂量（2.2毫克/千克）完全在规定范围内，这表明产妇能够控制自己的需求。该装置在分娩过程中似乎是可接受且安全的。该装置可能在镇痛药的比较研究中具有价值。
