Fraser I D, Bothamley J E, Bennett M O, Airth G R
Lancet. 1976 Jan 3;1(7949):6-8. doi: 10.1016/s0140-6736(76)92906-8.
Intensive antenatal plasmapheresis can significantly lower Rh-antibody levels in the blood of mothers carrying babies severely affected with rhesus haemolytic disease. Twenty-seven out of forty-four mothers were successfully delivered of babies that survived, after being treated with a combination of plasmapheresis and intrauterine transfusions. A further 52 mothers were treated by plasmapheresis along. When severe disease developed as an early stage in pregnancy the results were rather poor, but excellent results were obtained when severe disease developed relatively late in pregnancy. No serious complications were encountered in the mothers or babies.
强化产前血浆置换术可显著降低患有严重恒河猴溶血病胎儿的母亲血液中的Rh抗体水平。在接受血浆置换术和宫内输血联合治疗后，44名母亲中有27名成功分娩出存活的婴儿。另有52名母亲仅接受了血浆置换术治疗。当严重疾病在妊娠早期发展时，结果相当差，但当严重疾病在妊娠相对晚期发展时，则取得了优异的结果。母亲或婴儿均未出现严重并发症。
