Bonardello N M, de Gagliardi C G
Sabouraudia. 1979 Dec;17(4):371-6.
Intradermal tests were used to determine the extent of the endemic zone of coccidioidomycosis in Argentina. We performed our endemiological study among school-aged children and grown-ups in San Luis city and in the following towns: Nogoli, Villa de la Quebrada, Balde, Salinas del Bebedero, Beazley, Fraga and Eleodoro Lobos. We employed three coccidioidins for each person--Negroni's coccidioidin, coloured coccidioidin and uncoloured coccidioidin. Reactions were usually read 48 h after inoculation. After inoculating 1,262 individuals we could read only 1,069 results. Overall, the positive reactors to one, two or three coccidioidins were 14.8%. We found no relation between positive reactors and the sex of subjects, but every group showed a noticeable relation between age and positive reactions, especially in older people. The positive reactors for each of the coccidioidins were as follows: Negroni coccidioidin: 10.1%: coloured coccidioidin: 4.9% and uncoloured coccidioidin: 5.0%.
采用皮内试验来确定阿根廷球孢子菌病的流行区域范围。我们在圣路易斯市以及以下城镇的学龄儿童和成年人中开展了流行病学研究，这些城镇包括：诺戈利、维拉德拉克布拉达、巴尔德、贝韦德罗盐沼、比兹利、弗拉加和埃莱奥多罗·洛沃斯。我们为每个人使用了三种球孢子菌素——内格罗尼球孢子菌素、染色球孢子菌素和未染色球孢子菌素。通常在接种后48小时读取反应结果。在对1262人进行接种后，我们仅读取到1069份结果。总体而言，对一种、两种或三种球孢子菌素呈阳性反应的受试者占14.8%。我们发现阳性反应者与受试者的性别之间没有关联，但每个年龄组在年龄与阳性反应之间均呈现出显著的关联，尤其是在老年人中。每种球孢子菌素的阳性反应者比例如下：内格罗尼球孢子菌素：10.1%；染色球孢子菌素：4.9%；未染色球孢子菌素：5.0%。
