Schwartz A, Schulz E, Schober W
J Hirnforsch. 1979;20(4):445-52.
After lesioning the nucleus mediodorsalis and the nucleus anteromedialis thalami, where from specific afferents project to the cingulate cortex, we confirm signs of transneuronal degeneratiopn at lamina-V-pyramidal neurons of the cingulate cortex. By the GOLGI-KOPSCH-method operated animals show statistically significant decrease of dendritic spines at the apical main dendrites of lamina-V-pyramidal cells compared with the controls. The average spine-decrease along 300 micrometer length of the apical main dendrite amounts to 16%. Maximal spine-decrease is present at the central part of the apical main dendrite: 23% within a 50-micrometer-segment of this dendrite. This central dendritic part passes through the lamina III of the cingulate cortex. By the FINK-HEIMER-method degeneration particles are preferentially dispersed in laminae I, III and lower layers. The results give evidence for a more precise neuronal localization of the specific afferent terminations in this region.
在损毁丘脑背内侧核和丘脑前内侧核后（来自特定传入神经的纤维投射到扣带回皮质），我们证实了扣带回皮质第V层锥体细胞存在跨神经元变性的迹象。通过高尔基-科普施方法处理的动物与对照组相比，第V层锥体细胞顶主树突上的树突棘在统计学上有显著减少。沿着顶主树突300微米长度的树突棘平均减少量为16%。树突棘减少最多的部位在顶主树突的中部：在该树突的50微米节段内减少23%。这个树突中部穿过扣带回皮质的第III层。通过芬克-海默方法，变性颗粒优先分散在第I层、第III层和下层。这些结果为该区域特定传入终末的更精确神经元定位提供了证据。
